Author
Brown UniversityORCID 0000-0002-4060-4277Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Elizabeth C. Ding, Maximilian P. Pinho-Schwermann, Shengliang Zhang…·Wafik S. El‐Deiry
This study shows that ONC201 is effective against prostate cancer and small cell lung carcinoma cells, regardless of neuroendocrine differentiation markers or BRN2 overexpression.
William J. MacDonald, Praveen R. Srinivasan, Maximilian P. Pinho-Schwermann…·Wafik S. El‐Deiry
This study shows that inhibiting ITGB6 enhances anti-tumor immune responses in mouse models of head and neck and pancreatic cancers, with potential for combination immunotherapy.
Connor Purcell, Praveen R. Srinivasan, Maximilian P. Pinho-Schwermann…·Wafik S. El‐Deiry
This study investigates whether neuroendocrine differentiation (NED) affects sensitivity to imipridones ONC201 and ONC206 in prostate cancer cell lines, finding differential responses based on SOX2 and BRN2 overexpression.
Maximilian P. Pinho-Schwermann, Connor Purcell, Lindsey Carlsen…·Wafik S. El‐Deiry
This study shows that androgen receptor inhibitors enhance NK cell-mediated killing of prostate cancer cells and sensitivity to NKG2A checkpoint blockade by upregulating HLA-E expression.