Thomas C. Register

The paper identifies a molecular signature of age-related decline in vervet monkey skeletal muscle through multi-omics analysis, highlighting miRNA and epigenetic changes associated with sarcopenia.

This paper shows serum pro-N-cadherin levels correlate with cardiac fibrosis and diastolic dysfunction in irradiated non-human primates, suggesting it as a potential biomarker for radiation-related heart disease.

The paper develops and validates AI-based aging resilience biomarkers in non-human primates using longitudinal clinical data from baboons and rhesus macaques.

This study identifies age-related metabolic shifts in baboon hearts that promote glycosaminoglycan accumulation via the hexosamine biosynthetic pathway, preceding cardiac hypertrophy.

The paper integrates multi-omics data from female baboons to identify age-related molecular changes in the prefrontal cortex, revealing altered signaling pathways and potential biomarkers for age-related cognitive decline.

This study shows Mediterranean diets reduce neuroinflammation and protect brain structure and behavior in nonhuman primates by altering gene expression in the temporal cortex.

The paper quantifies age-related changes in regulatory and functional proteins in baboon adrenal zonae, finding decreased ZF function and less marked ZR function with age.

The paper analyzes synaptic molecular changes in Alzheimer's disease and related conditions using mass cytometry and imaging, identifying disease-specific molecular differences.

This study examines how Western and Mediterranean diets affect monocyte gene expression and social behavior in macaques, finding proinflammatory gene changes and behavioral differences.

The paper examines how diet and psychosocial stress affect brain anatomy in nonhuman primates, finding that Western diet increases AD-related brain regions while Mediterranean diet may protect against them.