Emma L. Fritsch

This study evaluates how aging affects the distribution and gene silencing activity of lipid-siRNA conjugates in the cerebrospinal fluid of mice.

This study examines the relationship between sleep patterns and anhedonia in male mice exposed to early-life stress, finding significant correlations between sleep architecture and anhedonic phenotypes.

This study develops a lipid-siRNA conjugate that uses perivascular transport to achieve long-lasting gene knockdown in the CNS without toxicity.

This study investigates how PACAP and CRF, two stress peptides, affect sleep architecture in mice, finding distinct impacts on sleep stages and behavior.

This study shows that early-life stress in male mice reduces response bias for highly rewarded stimuli in a translational reward task, suggesting potential parallels with human depression.