Mtor/Rptor Function Globally Prevents Cortical Microcephaly and Cell-autonomously Promotes Postnatal Neuron Survival in Cell Type Specific Manner
Ana Villalba, Robert Beattie, Florian M. Pauler…·Simon Hippenmeyer
This study investigates the role of Mtor/Rptor in cortical development, finding that its loss causes microcephaly through tissue-wide effects, while cell-autonomous Rptor function is critical for postnatal neuron survival in a cell-type-specific manner.