Characterization of Histone Lysine β-hydroxybutyrylation in bovine tissues, cells, and cumulus-oocyte complexes
Juliano Rodrigues Sangalli, Ricardo Perecin Nociti, Maite del Collado…·Flávio Vieira Meirelles
The paper investigates the effects of beta-hydroxybutyrate on histone lysine beta-hydroxybutyrylation and transcriptome changes in bovine fibroblasts and cumulus-oocyte complexes, showing altered gene expression but no impact on oocyte meiotic competence.