Author

Vaibhav Murthy

Oregon Health & Science UniversityORCID 0000-0002-4171-2296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:imaging· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1

Frequent Co-Authors

Alexander E. DaviesiD· 4 shared Jeremy CoppermaniD· 4 shared Carol M. R. Halsey· 2 shared Elise C. ManaloiD· 2 shared Francis Anderson· 2 shared Rawan MakkawiiD· 2 shared Ting ZhengiD· 2 shared Amy Gross· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersCancer Biology

Alexander E. DaviesORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 2, 2026

Spatially coordinated RTK-ERK signaling dynamics shape osteosarcoma single-cell drug response in the lung microenvironment

Rawan Makkawi, Carol M. R. Halsey, Vaibhav Murthy…·Alexander E. Davies

This study identifies FGFR-ERK signaling as a driver of adaptive resistance in osteosarcoma lung metastases and shows that combinatorial RTK inhibition enhances MCL1 inhibitor efficacy.

DOI 10.64898/2026.09.30.755770

humanimaging

𝕏 PostBluesky

BioengineeringbioRxivPreprintAug 4, 2026

A Compact, Standalone & Battery-Powered 3D Organoid-on-Chip System with Programmable Flow Control

Raviraj Thakur, Vaibhav Murthy, Samuel Olsen…·Alexander E. Davies

The paper introduces a compact, battery-powered organoid-on-chip system with programmable flow control, validated for culturing pancreatic cancer organoids and showing enhanced proliferation and drug response.

DOI 10.64898/2026.08.02.742326

mouseorganoid / primary culture

𝕏 PostBluesky

Cell BiologyCell SystemsPeer-reviewedApr 2, 2026

Single-cell morphodynamical trajectories enable prediction of gene expression accompanying cell state change

Jeremy Copperman, Ian C. McLean, Sean M. Gross…·Laura M. Heiser

The paper develops MMIST, a computational approach linking live-cell morphodynamics to gene expression changes during cell state transitions.

8 citations

imagingbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 8, 2025

Serial Imaging of Tumour and microEnvironment (SITE) platform for live-cell ex vivo modelling of primary and metastatic cancer dynamics

Vaibhav Murthy, Rawan Makkawi, Francis Anderson…·Alexander E. Davies

The paper introduces the SITE platform for live-cell ex vivo modeling of cancer and TME interactions, revealing tissue-specific dynamics and ERK signaling patterns in breast cancer.

3 citations

humanimaging

𝕏 PostBluesky