Fabien Pierrel

This study identifies UbiB as an ATP-dependent decarboxylase in bacterial ubiquinone biosynthesis, showing it can replace the UbiX/UbiD system in Escherichia coli.

This paper introduces a semi-quantitative HPLC-MS/MS method for detecting isoprenoid quinones in wastewater sludges, identifying 57 quinones across treatment stages.

COCOA-Tree reanalyzes coevolution datasets to uncover evolutionary properties of coevolving residues and shows different metrics identify distinct groups.

This study maps the distribution of isoprenoid quinones in Bacteria using genomic data and phylogenetic analysis, revealing new insights into their evolutionary history and metabolic adaptations.

This study shows that freshwater sponges acquired the microbial gene rquA via lateral gene transfer, enabling rhodoquinone biosynthesis and adaptation to hypoxia.

The paper identifies a novel ancestral high redox potential quinone, methyl-plastoquinone, and shows its evolutionary origin predates the Great Oxygenation Event.

This study identifies COQ4 as catalyzing the oxidative decarboxylation of the C1 carbon in CoQ biosynthesis in eukaryotic cells.