Dirk Eggink

This study shows that A/H3N2 influenza virus evolves differently in independent human airway cultures, with limited parallelism and novel mutations, suggesting evolutionary paths are influenced by selective context rather than intrinsic constraints.

This study characterizes the emergence and antigenic properties of influenza A(H3N2) viruses with N158K and K189R substitutions, showing they are antigenically distinct from vaccine strains and may reduce vaccine effectiveness.

This paper develops a stop-and-go chemoenzymatic method to synthesize asymmetrical bi-antennary glycans and uses them to study receptor binding evolution of human influenza A viruses.