Fei Ye

This study presents the cryo-EM structure of DISC1, revealing its homotetrameric architecture and its ability to bind multiple partner proteins.

The paper presents a cryo-EM conformational heterogeneity challenge to evaluate and improve methods for analyzing molecular motions in heterogeneous samples.

The paper evaluates pre-trained language models for antibody tasks, introduces an evaluation benchmark, and investigates their performance and benefits in real-world applications.