Michael W. Vieth

This study investigates the role of Helicobacter pylori gamma-glutamyltransferase (gGT) in gastric colonization and identifies compensatory mechanisms when gGT is absent.

This study identifies KRAS mutation as a driver of invasive gastro-esophageal adenocarcinoma in a mouse model, showing its synergistic role with Tp53 or Rb1 loss and potential as a therapeutic target.

This study identifies RNF43 mutations as a driver of colitis-associated cancer by showing their role in promoting inflammation and dysbiosis in mouse models and human patients.