Marisol Sampedro Castañeda

This study identifies CDKL5 as a kinase that phosphorylates Cav2.3, altering its function and contributing to neuronal excitability in CDKL5 deficiency disorder.

The paper maps the regulatory landscape of neuronal and glial differentiation in the enteric nervous system using single-cell RNA sequencing and identifies gene modules and epigenetic memory associated with neurogenesis and gliogenesis.