Author

Itay Y. Rousso

Ben-Gurion University of the NegevORCID 0000-0002-4399-9171Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:structural biology· 1

Frequent Co-Authors

Akshay DeshpandeiD· 2 shared Ashwanth Christopher FrancisiD· 2 shared Christopher AikeniD· 2 shared Jun HongiD· 2 shared AidanDarian W Douglas· 1 shared Alexander J. BryeriD· 1 shared Cameron M. TorresiD· 1 shared Conall Mc GuinnessiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

Akshay DeshpandeORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 3, 2025

The host protein cyclophilin A inhibits HIV-1 nuclear entry by decreasing capsid elasticity

Jun Hong, Akshay Deshpande, Yatish Thakare…·Christopher Aiken

This study shows that cyclophilin A inhibits HIV-1 nuclear entry in mutants by reducing capsid elasticity, which is reversed by suppressor mutations.

2 citations

humanexperimental assay

𝕏 PostBluesky

BiophysicsPLoS PathogensPeer-reviewedSep 11, 2024

Elasticity of the HIV-1 Core Facilitates Nuclear Entry and Infection

Akshay Deshpande, Alexander J. Bryer, Jonathan R. Andino-Moncada…·Itay Y. Rousso

This study shows that HIV-1 core elasticity is essential for nuclear entry and infection, with capsid-targeting drugs reducing elasticity and impairing infectivity.

42 citationstop 3%

humanstructural biology

𝕏 PostBluesky