Author

Guoli Zhou

Michigan State UniversityORCID 0000-0002-4497-5366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Hanne Mette HoffmanniD· 2 shared Alexandra M. YawiD· 1 shared Aneesh Sai Cherukuri· 1 shared Aritro SeniD· 1 shared Bharat PrajapatiiD· 1 shared Cara Detrie· 1 shared Duong NguyeniD· 1 shared Faraz RashidiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBioinformatics

Hanne Mette HoffmannORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 29, 2026

Placental pathology, circadian biology, and pathogenesis of spontaneous preterm birth: a pilot study of human placental gene expression profiling using a targeted HTG transcriptome panel

Guoli Zhou, Hanne Mette Hoffmann, Hidemi S. Yamamoto…·Raina Nakova Fichorova

This study identifies transcriptomic signatures in sPTB placentas, revealing suppressed metabolic and immune pathways, upregulated inflammatory and hypoxic pathways, and circadian dysregulation linked to preterm birth.

DOI 10.64898/2026.06.23.734020

humanbulk RNA-seq

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PhysiologyMolecular MetabolismPeer-reviewedOct 17, 2025

Interaction between time-of-day and oxytocin efficacy in mice and humans with and without gestational diabetes

Thu Van-Quynh Duong, Alexandra M. Yaw, Guoli Zhou…·Hanne Mette Hoffmann

The paper investigates how time-of-day and Bmal1 affect oxytocin efficacy in mice and humans with gestational diabetes, finding time-dependent effects and suggesting morning Pitocin administration for diabetic pregnancies.

5 citations

mousehuman

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ImmunologyProceedings of the National Academy of SciencesPeer-reviewedAug 4, 2025

Immuno-Responsive Gene-1: The Mitochondrial Key to Th17 Cell Pathogenicity in CNS Autoimmunity

Mohammad Nematullah, Mena Fatma, Guoli Zhou…·Shailendra Giri

This study identifies Irg1 as a protective gene that negatively regulates pathogenic Th17 cells in CNS autoimmunity using knockout mice and single-cell RNA sequencing.

2 citations

mousebulk RNA-seq

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