Martin Klingenspor

This study shows that deleting Adgrf5 in endothelial cells of brown adipose tissue impairs thermogenic capacity during prolonged cold exposure by inducing EndMT and fibro-inflammatory changes.

This study uses label-free metabolic imaging to analyze fat tissue remodeling at the single-cell level and introduces an AI tool for phenotypic assessment.

The paper develops an in vitro model of human subcutaneous adipocyte spheroids to study mitochondrial dysfunction and test mitochondria-activating compounds in obesity.

Shiny-Calorie provides a flexible, open-source tool for analyzing and visualizing indirect calorimetry data, supporting standardized integration and statistical analysis of metabolic phenotyping datasets.

This study identifies the dual role of the HPA axis in regulating energy homeostasis during cold exposure through ACTH-mediated thermogenesis and glucocorticoid-driven hyperphagia.

cOmicsArt provides a customizable tool for omics analysis and reporting, integrating GUI-based analysis with R for reproducibility and customization.

This paper introduces Metadatasheet, a metadata standard designed to improve data management by aligning with the data-lifecycle and enabling structured metadata recording in Microsoft Excel.

This study investigates how secretin induces satiation by modulating brain glucose metabolism and neural activity through the BAT-brain axis in humans.

The paper establishes a novel brown adipocyte cell line from defined murine precursors that can differentiate without PPARg agonists and respond to norepinephrine.