Author

Nadia Luheshi

AstraZeneca (United Kingdom)ORCID 0000-0002-4530-5188Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Angela L. Hughson· 2 shared David C. LinehaniD· 2 shared Gary HannoniD· 2 shared Laura Maria CalviiD· 2 shared Maggie L. LeschiD· 2 shared N. A. SalamaiD· 2 shared Scott A. GerberiD· 2 shared Tara G Vrooman· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Angela L. Hughson

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologyOncoImmunologyPeer-reviewedJun 5, 2026

Local delivery of SBRT and IL-12 to Murine PDAC Tumors Modulates Hematopoiesis

Tara G Vrooman, Emily R. Quarato, Gary Hannon…·Scott A. Gerber

This study shows that local delivery of SBRT and IL-12 to PDAC tumors in mice affects bone marrow hematopoiesis, causing both acute and long-term changes.

DOI 10.1080/2162402x.2026.2682058

mouseexperimental assay

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Cancer BiologyMolecular Therapy — Nucleic AcidsPeer-reviewedSep 30, 2024

Local Delivery of SBRT and IL12 by mRNA Technology Overcomes Immunosuppressive Barriers to Eliminate Pancreatic Cancer

Angela L. Hughson, Gary Hannon, N. A. Salama…·Scott A. Gerber

This paper demonstrates a combination treatment of SBRT and IL-12 mRNA in murine pancreatic tumors, achieving cures in both primary and metastatic models by enhancing T cell responses.

22 citations

mousebulk RNA-seq

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