Conditioning electrical stimulation enhances functional rewiring in a mouse model of nerve transfer to treat chronic spinal cord injury
Juan Sebastián Jara, Marwa Soliman, Amanda Bernstein…·Edmund R Hollis II
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Weill Cornell MedicineORCID 0000-0002-4535-4668Unclaimed ORCID profile · follow to get notified of new preprints
9 papers
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Juan Sebastián Jara, Marwa Soliman, Amanda Bernstein…·Edmund R Hollis II
Abel Torres Espin, Amanda Bernstein, Marwa Soliman…·Edmund R Hollis II
The paper introduces a kinematic deviation index (KDI) to assess forelimb function in rodents, demonstrating its ability to detect movement differences and response to interventions.
Xiaofei Guan, Yanjie Zhu, Jian Zhong, Edmund R Hollis II
This study identifies CST-targeted spinal interneurons as a key circuit in chronic neuropathic pain following CNS injury in mice.
Jaclyn T. Eisdorfer, Sherry Lin, Joshua K. Thackray…·Victoria E. Abraira
This study uses motion sequencing to analyze behavioral syllables after spinal cord injury, revealing recovery patterns shaped by injury severity and individual differences.
This study shows that nicotinic signaling is necessary for motor learning but not for rehabilitation of previously learned movements after spinal cord injury.
This study shows that cholinergic neurons in the basal forebrain are essential for acquiring coordinated motor skills in mice, but not for executing learned tasks.
Najet Serradj, Francesca Marino, Yunuen Moreno-López…·Edmund R Hollis II
This study investigates how corticospinal neuron activity changes during skilled versus unskilled motor learning and shows that patterned network activity is essential for skilled movement execution.
Ashley L. Kalinski, Choya Yoon, Lucas D. Huffman…·Roman J. Giger
This study identifies efferocytosis as a key mechanism for nerve debridement following sciatic nerve injury through single-cell RNA-sequencing and genetic analysis.
Hisham Mohammed, Yue Li, Paola di Grazia…·Edmund R Hollis II
The paper introduces a modified single pellet reach task to assess forelimb dexterity in mice and shows that cortical inactivation affects different motor components at distinct times.