Author

Cèsar Sierra

Barcelona Institute of Science and TechnologyORCID 0000-0002-4544-9149Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Mara DiersseniD· 3 shared Alfonsa Zamora‐MoratallaiD· 2 shared Álvaro Fernández‐BlancoiD· 2 shared Miguel Sabariego-NavarroiD· 2 shared Carlotta Viana· 1 shared Cristina Rodríguez-MariniD· 1 shared Davide NormannoiD· 1 shared Dominic S. Yap· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersNeuroscience

Mara DierssenORCID

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3 papers

Recent·Most cited

Molecular BiologyiSciencePeer-reviewedSep 30, 2026

HDAC inhibitor treatment restores transcriptome, chromatin accessibility and memory deficits in a mouse model for Down syndrome

Cèsar Sierra, René A. J. Crans, Mara Dierssen

DOI 10.1016/j.isci.2026.117670

mousebulk RNA-seq

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NeuroscienceRepositori digital de la UPF (Universitat Pompeu Fabra)Peer-reviewedJan 1, 2025

A highly conserved neuronal microexon in DAAM1 controls actin dynamics, RHOA/ROCK signaling, and memory formation

Patryk Poliński, Marta Miret-Cuesta, Alfonsa Zamora‐Moratalla…·Manuel Irimia

4 citations

mousestatistical model

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NeuroscienceMolecular PsychiatryPeer-reviewedFeb 26, 2024

Single nucleus RNA-seq in the hippocampus of a Down syndrome mouse model reveals new key players in memory

Cèsar Sierra, Miguel Sabariego-Navarro, Álvaro Fernández‐Blanco…·Mara Dierssen

The paper uses single nucleus RNA-seq to analyze the hippocampus of a Down syndrome mouse model, identifying transcriptomic changes and a novel long-non-coding gene involved in cognitive phenotypes.

31 citationstop 1%

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