Yan Liu

This study identifies myeloid HIF-1 as a driver of pulmonary fibrosis by sustaining hypoxic fronts and promoting fibroblast activation and matrix remodeling.

This study identifies molecular mechanisms regulating PDE11A4 liquid-liquid phase separation and shows that PDE11A inhibitors can reverse it in cells and brain.

This study develops a new humanized GVHD model and shows that Echinomycin, a HIF1 inhibitor, reduces GVHD symptoms and extends survival in mice.