Susanne Bechstedt

This study identifies CKAP2 and CKAP2-Like as axonemal microtubule-associated proteins that regulate ciliogenesis in human cells, with distinct roles in ciliary length and function.

This study shows that EML3 is essential for embryonic growth and cortical development, with its absence causing cobblestone brain malformation due to disrupted pial basement membrane structure.

The paper identifies Aurora A/TPX2 as CKAP2 interactors and shows Aurora A phosphorylates CKAP2, reducing its microtubule affinity and affecting spindle growth.

This study shows that an intrinsically disordered domain of CKAP2 can catalyze microtubule polymerization and depolymerization, challenging the requirement for a stable structure in enzymatic activity.

This study identifies Maspin as a cytoskeleton-binding protein that modulates cell shape and prevents epithelial-mesenchymal transition by interacting with microtubules and microfilaments.

This study identifies CKAP2 as a microtubule growth factor that regulates microtubule dynamics and ensures accurate chromosome segregation, with its loss leading to segregation errors and aneuploidy.

This paper shows TPPP forms liquid condensates and aggregates in Multiple System Atrophy, linking its condensate property to microtubule nucleation and disease pathology.