Author

Tim R. Fenton

University of KentORCID 0000-0002-4737-8233Unclaimed ORCID profile · follow to get notified of new preprints

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Tim R Fenton1 paper

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ian G. ReddiniD· 2 shared Alex BoussioutasiD· 1 shared Allan BradleyiD· 1 shared Andrea NistiD· 1 shared Ane Stranger· 1 shared Ankur ChakravarthyiD· 1 shared Catherine L. Harper-WynneiD· 1 shared Dan Liu· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

Ian G. ReddinORCID

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3 papers

Recent·Most cited

Cancer BiologyCancer LettersPeer-reviewedApr 27, 2025

Resistance patterns in drug-adapted cancer cell lines reflect complex evolution in clinical tumors

Helen E. Grimsley, Magdalena Antczak, Ian G. Reddin…·Martin Michaelis

This study identifies drug-resistant sublines of TNBC cell lines and finds that resistance mechanisms are unique and unpredictable, suggesting new potential drug targets.

9 citations

humanwhole-exome sequencing

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Cancer BiologybioRxivPreprintJul 30, 2024

Human-like APOBEC3 gene expression and anti-viral responses following replacement of mouse Apobec3 with the 7-gene human APOBEC3 locus

Nerissa K Kirkwood, Haydn M Prosser, Melvyn W Yap…·Tim R Fenton

This study creates a mouse model with human APOBEC3 genes to study their expression and anti-viral functions, showing human-like regulation and functional responses.

DOI 10.1101/2024.07.30.605801

mouseexperimental assay

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GenomicsbioRxivPreprintJan 27, 2020

Molecular and cellular heterogeneity of gastric cancer explained by methylation-driven key regulators

Seungyeul Yoo, Quan Chen, Li Wang…·Jun Zhu

The paper identifies 11 methylation-driven key regulators in gastric cancer and shows they contribute to tumor heterogeneity and clinical outcomes.

6 citations

humanDNA methylation

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