Suliana Manley

The paper identifies MTERF1 as a suppressor of mtDNA deletion pathologies by showing its loss enhances mitochondrial function through transcriptional relief.

The paper investigates asymmetric mitochondrial trafficking in cultured cells, showing it maintains mitochondrial network morphology by balancing perinuclear biogenesis.

The paper shows that mitochondrial DNA nucleoid distribution is controlled by pearling and cristae structure, revealing a mechanism for nucleoid spacing and segregation.

This paper introduces qExM, a method to estimate endogenous protein abundance in expanded samples, achieving a 9.4% mean percent error in nuclear pore complex subunit stoichiometry.

This paper introduces hybrid-EDA, a microscopy framework that reduces phototoxicity while capturing rare biological events using event-driven fluorescence acquisitions.

This study identifies a biophysical mechanism for mitochondrial pearling, showing it occurs spontaneously in various cell types and is driven by internal pressure or external tension.

Spotiflow improves spot detection in microscopy images using deep learning, achieving subpixel accuracy and efficiency across diverse datasets.

This study models mitochondrial network dynamics using simulations and analytic models to show how local parameters control network morphology and remodeling rates.

This paper describes surface passivation and functionalization methods for interferometric scattering microscopy to reduce non-specific binding and enable single-molecule experiments.

Enso decodes bacterial cell cycle and cell type from static SMLM images using unsupervised deep learning without prior knowledge.

The paper investigates how NF-kB (p65) DNA binding time relates to transcriptional activation by analyzing mutants affecting DNA binding and protein-protein interaction domains.