Author

Alastair Morris Kilpatrick

MRC Centre for Regenerative MedicineORCID 0000-0002-4795-8799Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 3 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Laura J. WagstaffiD· 2 shared Alasdair Grant RooneyiD· 1 shared Anna WilliamsiD· 1 shared Bahar Mirshekar-SyahkaliD· 1 shared Berthold GöttgensiD· 1 shared Camille MaloufiD· 1 shared Catalina A. VallejosiD· 1 shared Charles ffrench‐ConstantiD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Laura J. WagstaffORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedMay 22, 2023

Marked regional glial heterogeneity in the human white matter of the central nervous system

Luise A. Seeker, Nadine Bestard-Cuche, Sarah Jäkel…·Anna Williams

The paper identifies regional glial heterogeneity in human white matter using single nucleus RNA sequencing, revealing tissue-specific glial populations and age/sex-related gene expression differences.

66 citationstop 2%

humanscRNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 13, 2023

Electroconvulsive stimuli reverse neuro-inflammation and behavioral deficits in a mouse model of depression.

Alasdair Grant Rooney, Alastair Morris Kilpatrick, Charles ffrench‐Constant

The paper shows electroconvulsive stimuli reverse neuro-inflammation and behavioral deficits in a mouse depression model by identifying molecular pathways and genes involved in recovery.

DOI 10.1101/2023.05.13.540577

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintSep 13, 2021

p57Kip2 regulates embryonic haematopoietic stem cell numbers by controlling the size of the sympathoadrenal progenitor pool

Chrysa Kapeni, Leslie Nitsche, Alastair Morris Kilpatrick…·Katrin Ottersbach

The paper shows p57Kip2 limits HSC numbers by restricting SNS progenitor size and catecholamine secretion in the AGM region via β2-adrenergic signaling.

DOI 10.1101/2021.09.13.459835

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedJan 21, 2021

Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun

Laura J. Wagstaff, Jose Antonio Gomez-Sanchez, Shaline V. Fazal…·Kristján R. Jessen

The paper shows that restoring Schwann cell c-Jun rescues nerve regeneration failures in aging and chronic denervation by enhancing regenerative support.

133 citationstop 1%

mouseexperimental assay

𝕏 PostBluesky