Capucine Trollet

This study identifies age-related changes in the muscle secretome that impair stem cell function through sphingolipid metabolism alterations.

The paper identifies EMILIN1 as a TGFβ/SETDB1-regulated secreted biomarker in DMD, showing its role in fibrosis and myogenesis through proteomic analysis of patient-derived myotubes.

This study identifies collagen VI as a conserved pro-fibrotic factor that impairs muscle regeneration in three distinct human myopathies.

This study compares the effects of endurance and resistance exercise on OPMD skeletal muscle in mice, finding that resistance exercise reduces PABPN1 aggregates and reverses muscle atrophy, while endurance exercise increases aggregates and collagen deposition.

This study shows that guanabenz acetate reduces PABPN1 aggregates and improves muscle function in an OPMD mouse model by modulating the UPR.