Ye Sing Tan

This study identifies GFAP as a novel mediator of mitochondrial fission by surrounding fission sites and modulating Drp1 recruitment, revealing a new mechanism in mitochondrial plasticity.

This study shows that loss of IVNS1ABP causes a progeroid neuropathy by impairing proteostasis, leading to protein aggregation and lysosomal dysfunction in neuronal cells.

This study identifies a GPCR signaling pathway in astrocytes that regulates F-actin remodeling and NSC reactivation through Mrtf nuclear translocation.

This study shows that Arl2 regulates mouse cortical development by promoting microtubule growth through its interaction with Cdk5rap2.

This study identifies Msps/XMAP215 as a regulator of acentrosomal microtubule assembly in quiescent Drosophila NSCs, which is essential for E-cadherin localization and NSC reactivation.

This study shows that Parafibromin/Hyrax regulates cell polarity and centrosome assembly in neural stem cells, preventing overgrowth and tumour formation.