Paulo Kofuji

The paper identifies a spatial threshold for astrocyte calcium signal propagation in mice, which determines gliotransmitter release and synaptic modulation.

The paper shows that two endocannabinoids, 2-AG and AEA, signal to different cell types (neurons and astrocytes), inducing distinct synaptic regulation mechanisms.

This study shows that altered calcium signaling in Bergmann glia contributes to the electrophysiological changes in Purkinje cells in SCA1 mice, suggesting a therapeutic target for treatment.

The paper reveals column- and layer-specific astrocyte-mediated non-synaptic communication between cortical neurons through CB1R activation and ATP/adenosine release.