Ali G. Turhan

This paper describes a novel low-shear stress bioreactor for expanding NK-92 cells, showing improved cell growth and viability compared to traditional methods.

The paper analyzes single-cell transcriptomic and epigenomic data from porcine blastocysts to identify gene regulatory dynamics in embryonic and extra-embryonic lineages during development.

The paper uses single-cell RNA sequencing and proteomics to analyze pig blastocyst development, identifying new cell subpopulations and regulatory networks.

The paper identifies cells with hematopoietic stem cell (HSC) transcriptome features in human fetal kidneys and iPSC-derived kidney organoids.

The paper shows that chronic myeloid leukemia patients in molecular remission still have widespread aberrant alternative splicing, unlike normal gene expression and DNA methylation patterns.

This paper describes a method to convert adult hepatocytes into LGR5+ endodermal progenitor cells using transcription factors and activators, enabling liver tissue regeneration and disease modeling.

The paper generates c-met-mutated iPSC-derived kidney organoids that recapitulate genomic and phenotypic features of PRCC, identifying common genes and validating their expression in both organoids and patient tumors.