Alon Monsonego

This study shows that time-restricted feeding improves glucose intolerance and circadian disruption caused by weight cycling in young obese mice, but not in mid-aged mice.

This study shows that mid-aged mice normalize dysglycemia faster than young mice when reversing obesity, but their hypothalamic microgliosis worsens after diet reversal.

This study shows CD4 T cells differentiate into cytotoxic T cells in senescent-rich environments, and reducing senescent cells halts this differentiation, impacting aging and disease.

This study shows TGFβ profoundly regulates T-cell size and physiology by modulating gene expression and transcription factor networks, independent of other cytokines.

CausalCell applies causal discovery to single-cell data to infer causal interactions, addressing challenges in algorithm design and evaluation for this task.