Author

Hajo Kries

Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)ORCID 0000-0002-4919-2811Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein design· 1

Frequent Co-Authors

Philipp Stephan· 2 shared Chloe LangleyiD· 1 shared Daniela WinkleriD· 1 shared Hsin-Mei Huang· 1 shared J. BasquiniD· 1 shared Lorenzo CaputiiD· 1 shared Sarah Ellen O'ConnoriD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersSynthetic Biology

Philipp Stephan

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2 papers

Recent·Most cited

Synthetic BiologyAngewandte Chemie International EditionPeer-reviewedJun 16, 2023

Directed evolution of piperazic acid incorporation by a nonribosomal peptide synthetase

Philipp Stephan, Chloe Langley, Daniela Winkler…·Hajo Kries

The paper reports directed evolution of an NRPS adenylation domain to incorporate piperazic acid, demonstrating that low-throughput methods can alter NRPS substrate specificity.

24 citations

experimental assay

𝕏 PostBluesky

Synthetic BiologyCell chemical biologyPeer-reviewedNov 24, 2020

Engineering DNA templated nonribosomal peptide synthesis

Hsin-Mei Huang, Philipp Stephan, Hajo Kries

This paper describes the engineering of DNA-templated nonribosomal peptide synthetases (DT-NRPS) to enable covalent intermediate channeling and improved catalytic efficiency in biosynthesis.

35 citations

experimental assayprotein design

𝕏 PostBluesky