Nicolas Blanchard

The paper uses single-cell RNA sequencing to analyze immune cell interactions in asymptomatic and symptomatic malaria patients, finding reduced monocyte-T cell interactions and increased inflammation in symptomatic cases.

This study shows chronic IL-1 signaling in hippocampal neurons causes DNA double-strand breaks, leading to cognitive deficits in mice infected with Toxoplasma gondii.

This study shows that latent Toxoplasma gondii infection reduces visceral nociception in mice via peripheral opioid receptor signaling, suggesting a potential negative link with abdominal pain in humans.

This study identifies the protective functions and differentiation cues of brain-resident CD8+ T cells during chronic Toxoplasma gondii infection using a mouse model and single-cell transcriptomics.