Ian R.L. Smith

This study uses nMOST to profile proteo-lipidomics in lysosomal storage disease mutants, revealing autophagy defects and mitochondrial dysfunction.

The paper introduces a method to coisolate and fragment SILAC peptide pairs for improved identification and quantification in MS/MS-based proteomics.

The paper introduces a proteomic technology called Miro to identify amino acid substitutions that affect protein function by using mistranslation and mass spectrometry.

The paper identifies phosphosites that affect protein thermal stability by measuring stability differences between proteins and their phosphorylated forms at a proteomic scale.