Danna R. Gifford

This study examines how extreme temperature exposure affects the demographic outcomes of Sulfolobus acidocaldarius, showing that mortality depends on cumulative exposure time rather than a fixed thermal threshold.

The study shows that fitness costs of antibiotic resistance mutations in rich media do not reliably predict their costs in infection-like environments, with increased costs in lung-mimicking media and reduced prevalence in urinary tract-mimicking media.

The paper shows that host inflammatory environments constrain the loss of quorum sensing in Pseudomonas aeruginosa by linking it to oxidative stress and amino acid availability.

This study examines how the antimutator ΔnudJ in Escherichia coli reduces mutation rate and alters mutational spectrum, leading to decreased antibiotic resistance potential.

This paper introduces QMS-Seq, a high-throughput method to identify antibiotic resistance mutations in E. coli, revealing distinct mutation patterns for multi-drug and antibiotic-specific resistance.

This study shows that increased mutation rates in E. coli lead to more and more specific nitrofurantoin resistance mutations, raising concerns about the antibiotic's long-term effectiveness.

This study shows antibiotic resistance in Pseudomonas aeruginosa can both help and hinder its ability to invade respiratory microbiomes, depending on the commensal microbes involved.