Knight Cg

This paper develops a population sequencing pipeline to estimate mutation rates in E. coli under varying population densities, finding a strong negative association between density and mutation rates.

The paper shows that host inflammatory environments constrain the loss of quorum sensing in Pseudomonas aeruginosa by linking it to oxidative stress and amino acid availability.

This study examines how the antimutator ΔnudJ in Escherichia coli reduces mutation rate and alters mutational spectrum, leading to decreased antibiotic resistance potential.

This study shows that multiple toxins in T6SS limit resistance evolution in bacteria, similar to combination therapies in medicine.

This study identifies a mutation rate increase in a multi-azole resistant Aspergillus fumigatus clade, linking it to rapid antifungal resistance evolution.

This study identifies hydrogen peroxide detoxification as the mechanism behind density-dependent mutation rate plasticity in microbial populations.