Author

Sandhya S. Thomas

Baylor College of MedicineORCID 0000-0002-4993-8812Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Hongchun Lin· 2 shared Zhaoyong HuiD· 2 shared Farhard S Danesh· 1 shared Feng LiiD· 1 shared Hui PengiD· 1 shared Hui PengiD· 1 shared Jihong CheniD· 1 shared Meijun SiiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

Hongchun Lin

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2 papers

Recent·Most cited

Cell BiologyKidney InternationalPeer-reviewedJun 10, 2025

ROCK1 activates mitochondrial fission leading to oxidative stress and muscle atrophy

Meijun Si, Jihong Chen, Rizhen Yu…·Zhaoyong Hu

This study identifies ROCK1 activation as a driver of mitochondrial fission and oxidative stress in CKD-induced muscle wasting, showing pharmacological inhibition of ROCK1 can alleviate these effects.

12 citations

mousemetabolomics

𝕏 PostBluesky

Molecular BiologyJournal of Cachexia Sarcopenia and MusclePeer-reviewedJun 20, 2022

Decoding the transcriptome of denervated muscle at single-nucleus resolution

Hongchun Lin, Xinxin Ma, Yuxiang Sun…·Zhaoyong Hu

This study uses snRNA-seq to analyze denervated muscle, identifying transcriptional changes in specific myonuclei subtypes and revealing gene regulatory networks and metabolic shifts associated with muscle atrophy.

73 citationstop 4%

mousesnRNA-seq

𝕏 PostBluesky