Angus C. Wilson

This study shows METTL3 promotes human coronavirus replication without requiring interferon signaling.

The paper uses nanopore sequencing to show herpesvirus mRNAs have longer poly(A) tails than cellular or other viral transcripts, suggesting a unique mechanism for enhancing gene expression.

This study shows HSV-1 protein ICP4 increases nuclear fluidity to enable condensate formation, supporting viral replication.

This study examines how HSV-1 ICP4 expression in uninfected cells alters host gene expression through RNA-Seq, identifying differentially expressed genes and validating findings against infected cell data.

This study shows TDP-43 promotes HSV-1 replication in human DRG-derived neurons by enhancing viral mRNA splicing, but not in epithelial cells or fibroblasts.

The paper evaluates Dorado basecalling for nanopore DRS to detect m6A modifications in RNA, finding that stringent filtering improves accuracy and revealing cell-type differences in m6A proportions at conserved sites.

The paper develops a novel method for high-resolution transcriptome annotation from Nanopore DRS data, demonstrating its effectiveness on both synthetic and real datasets, including a new annotation of human adenovirus type F 41.

The paper uses direct RNA long-read sequencing to show m6A modifications on adenovirus RNA are necessary for efficient splicing.

The paper shows that Topoisomerase 2-dependent DNA damage and AKT phosphorylation dynamics regulate HSV-1 latency by integrating extracellular signals and nuclear DNA damage.