Kanako Hayashi

This paper develops a targeted nanotherapeutic, FA-2DG-D-Niclo, which delivers niclosamide to FRβ-expressing macrophages, reducing endometriosis lesions and hyperalgesia in mice.

This study shows that prenatal exposure to BPA or BPS at environmentally relevant doses disrupts germ cell programming across generations, affecting sperm counts and transcriptional and epigenetic changes in mice.

This study examines the transgenerational effects of perinatal cannabis exposure on female reproductive parameters in mice, finding limited impacts on reproductive function across generations.

This study shows that repeated endometriosis lesion inductions in mice increase neuroinflammation and central sensitization, leading to chronic pelvic pain.

This study examines age and sex differences in pharmacokinetics and acute behavioral effects of vaporized cannabis extract in mice using different solvents.

This study shows high-fat diets worsen endometriosis-related abdominal pain by increasing peritoneal inflammation and pain mediators.

The paper shows niclosamide improves peritoneal microenvironment in endometriosis by regulating macrophage dynamics and intercellular communication with B cells in a mouse model.