Coronavirus protein interaction mapping in bat and human cells identifies molecular and genetic switches for immune evasion and replication
Jyoti Batra, Magdalena Rutkowska, Yuan Zhou…·Nevan J. Krogan
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Icahn School of Medicine at Mount SinaiORCID 0000-0002-5052-588XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Jyoti Batra, Magdalena Rutkowska, Yuan Zhou…·Nevan J. Krogan
Rafael Fenutría, Laura Espinar‐Barranco, Rebecca E. Hamlin…·Ana Fernández-Sesma
This study compares DENV-2 and DENV-4 infection kinetics and immune responses in human tonsil histocultures, showing DENV-4 replicates faster and activates innate immunity more strongly.
Wendy Blay Puryear, Kaitlin Sawatzki, Nichola J. Hill…·Jonathan A. Runstadler
The paper reports an outbreak of H5N1 in New England seals, linking it to a second wave of H5N1 in wild birds and identifying genetic differences between avian and mammalian infections.