Systems BiologyCell Host & MicrobePeer-reviewed
Coronavirus protein interaction mapping in bat and human cells identifies molecular and genetic switches for immune evasion and replication
Jyoti Batra, Magdalena Rutkowska, Yuan Zhou…·Nevan J. Krogan
Author
Helene Foussard
Gladstone InstitutesORCID 0000-0002-5063-113XUnclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2026 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
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- Systems BiologyMolecular Systems BiologyPeer-reviewed
A proximity proteomics pipeline with improved reproducibility and throughput
Xiaofang Zhong, Qiongyu Li, Benjamin J. Polacco…·Ruth Hüttenhain
This paper introduces a scalable proximity proteomics pipeline that improves reproducibility and throughput in biotinylation-based spatial proteomics.
36 citationstop 1% - Systems BiologybioRxivPreprint
Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories
Mehdi Bouhaddou, Ann‐Kathrin Reuschl, Benjamin J. Polacco…·Nevan J. Krogan
The paper systematically analyzes proteomic and genomic data of SARS-CoV-2 variants to identify how mutations affect viral gene expression, host interactions, and immune evasion.
14 citations - Systems BiologyNaturePeer-reviewed✦ In-depth digest
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
David Ezra Gordon, Gwendolyn Μ. Jang, Mehdi Bouhaddou…·Natalia Jura
Affinity-purification mass spectrometry of 26 SARS-CoV-2 proteins in HEK293T cells yields 332 high-confidence host interactions and 67 druggable human proteins with known compounds.