Mats Ohlin

The paper develops methodologies to generate and analyze immunoglobulin loci variation in rhesus macaques, revealing extensive diversity and expanding existing allele sets by 60%.

This study shows that increasing Fc flexibility in an IgG1-IgG3 hybrid monoclonal antibody enhances opsonic function and protection against group A streptococci.

The paper curates high-quality human immunoglobulin germline gene reference sets to improve AIRR-seq analysis accuracy and facilitate immunoglobulin gene studies.