ImmunologyNature CommunicationsPeer-reviewed
The increased hinge flexibility of an IgG1-IgG3 hybrid monoclonal enhances Fc-mediated protection against group A streptococci
Arman Izadi, Yasaman Karami, Eleni Bratanis…·Pontus Nordenfelt
This study shows that increasing Fc flexibility in an IgG1-IgG3 hybrid monoclonal antibody enhances opsonic function and protection against group A streptococci.
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