Author
Harvard UniversityORCID 0000-0002-5125-9667Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Taral R. Lunavat, Lisa Nieland, Sanne M. van de Looij…·Koen Breyne
This study shows that delivering 4-1BBL via AAV enhances IL-12-induced anti-glioblastoma immunity in mouse models by boosting CD8 T cell activity and survival.
Shuqi Yun, Anil K. Chekuri, Jennifer Art…·Christiano R. R. Alves
This paper develops a CRISPR base editing strategy to correct the FD-causing mutation in human cells and mice, achieving up to 70% on-target correction and functional restoration.
Joana Ferreira da Silva, Connor J. Tou, Emily M. King…·Benjamin P. Kleinstiver
This paper introduces click editing, a genome writing platform that enables precise installation of genetic edits using DNA polymerases and HUH endonucleases, with minimal indels and no unwanted insertions.
Carina Henriques, Miguel Monteiro Lopes, Patrícia Maia Correia de Albuquerque…·Rui Jorge Nobre
This paper optimizes size exclusion chromatography (SEC) for isolating biologically active EV-AAVs for non-invasive brain gene delivery, showing higher recovery and transgene expression efficiency compared to differential ultracentrifugation.