Author

Ryan Seamus McGee

Washington University in St. LouisORCID 0000-0002-5142-7552Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Organism:yeast· 1

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Dmitri A. PetroviD· 1 shared Grant KinsleriD· 1 shared Mikhail TikhonoviD· 1 shared

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1 shared paperEvolutionary Biology

Dmitri A. PetrovORCID

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1 paper

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Evolutionary BiologyMolecular Biology and EvolutionPeer-reviewedJul 23, 2024

Improving the accuracy of bulk fitness assays by correcting barcode processing biases

Ryan Seamus McGee, Grant Kinsler, Dmitri A. Petrov, Mikhail Tikhonov

The paper develops a computational method to correct barcode processing biases in bulk fitness assays, improving fitness estimates in yeast variant libraries.

8 citations

yeastbulk RNA-seq

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