Edison Ong

The paper introduces the Vaccine Ontology (VO), a standardized framework for representing vaccines and related data, enhancing data integration and AI research.

This paper develops an mRNA-LNP vaccine, mRNA-1965, that clears HBV-infected hepatocytes in mice by inducing broad immune responses across HBV genotypes.

This study uses spatial transcriptomics to identify novel Pseudomonas aeruginosa virulence factors and host-pathogen interactions in ocular infection.

mtx-COBRA improves subcellular localization prediction for bacterial proteins, outperforming PSORTb in accuracy for proteins with unknown localization.

This study designs SARS-CoV-2 spike protein variants with enhanced immunogenicity by engineering T cell epitopes while preserving structure and function.

The paper predicts COVID-19 vaccine candidates using reverse vaccinology and machine learning, identifying the N and nsp3 proteins as potential targets.