Natalie M. Niemi

This study identifies OPA1's role in fatty acid release from lipid droplets and links its function to human metabolism.

This study identifies sequence elements that enable dual localization of mitochondrial proteins, showing how combinatorial features regulate import and function across compartments.

This study shows that sustained Pptc7 loss in adult mice causes skeletal muscle dysfunction and reduced body mass through BNIP3 dysregulation, with partial rescue by Bnip3 KO.

The paper identifies ARMC1 as a repressor of mitophagy that interacts with TMEM11, BNIP3, and NIX, and shows TMEM11 antagonizes PPTC7 to protect receptors during mitophagy activation.

This study quantifies presequence strength in mitochondrial protein import and shows its impact on mitochondrial function and cellular fitness.

This paper shows that PPTC7 limits mitophagy by interacting with BNIP3 and NIX, promoting their proteasomal degradation through dynamic, proximal associations.

The paper introduces exclusion-based immunoprecipitation methods to identify RNA binding partners of CRD-BP in mammary epithelial cells, showing enrichment in mRNAs related to mitochondrial function and oxidative stress.