Csaba Pál

The paper develops a framework to assess antibiotic resistance and virulence risks in pathogens, finding that resistance can increase virulence through genetic changes.

The paper identifies gut phages with adhesin proteins that bind epithelial cells and traffic to the endoplasmic reticulum, revealing potential interactions with the human virome.

This study creates a high-resolution morpho-proteomic atlas of mitosis by decomposing it into 40 subsections and quantifying 4,350 proteins, revealing dynamic changes and links to cancer mutations.

This paper develops a scalable framework for precision phage therapy by combining genomic surveillance and phage typing to target carbapenem-resistant Acinetobacter baumannii.

The paper systematically investigates solubility limits of Escherichia coli proteins upon overexpression, revealing that most insoluble proteins aggregate after folding and that high disorder content and low surface stickiness correlate with solubility.

This study demonstrates how ssDNA recombineering in bacteria enables hyper-diversification of nanobodies, resulting in variants that recognize new antigens while retaining original specificity.

The paper examines features of a cyanobacterial regulatory node for optogenetic device interoperability between E. coli and P. putida, identifying translational control as a bottleneck and proposing optimization strategies.

This study uses a chemical-genetic approach to analyze resistance determinants of E. coli to 15 AMPs, revealing cross-resistance and collateral sensitivity patterns.

This paper develops a CRISPR-interference system to silence bacterial mobile genetic elements, reducing their transposition rates and stabilizing synthetic constructs.

This study shows that enzyme promiscuity enables E. coli to adapt to novel substrates through computational modeling and lab evolution experiments.