Bálint Kintses

The paper develops a framework to assess antibiotic resistance and virulence risks in pathogens, finding that resistance can increase virulence through genetic changes.

The paper identifies gut phages with adhesin proteins that bind epithelial cells and traffic to the endoplasmic reticulum, revealing potential interactions with the human virome.

The paper defines a global map of receptor-binding protein compatibility for designing phages targeting Klebsiella and Acinetobacter species.

This paper develops a scalable framework for precision phage therapy by combining genomic surveillance and phage typing to target carbapenem-resistant Acinetobacter baumannii.

This study uses synthetic genomes to investigate how synonymous codon recoding affects organismal fitness and develops a workflow to overcome lethal effects of codon swaps.

The paper systematically investigates solubility limits of Escherichia coli proteins upon overexpression, revealing that most insoluble proteins aggregate after folding and that high disorder content and low surface stickiness correlate with solubility.

This study uses a chemical-genetic approach to analyze resistance determinants of E. coli to 15 AMPs, revealing cross-resistance and collateral sensitivity patterns.