Chloe L. Tayler

This paper introduces a plate-based ISD-SPE workflow for integrated proteome and secretome analysis of TLR signaling in macrophages, showing improved reproducibility and scalability for drug discovery.

The paper introduces dia-PASEF, a mass spectrometry workflow for rapid secretome profiling, revealing novel inflammatory responses and dynamic secretion patterns in macrophages.

This study evaluates two mass spectrometry-based phenotypic screening approaches for identifying anti-inflammatory compounds in macrophages and compares them to cytokine profiling.