Celia A. McKee

The paper develops an automated high-content imaging workflow to quantify synapse loss associated with amyloid beta plaques in mouse brains, finding that large cored plaques primarily drive synapse loss.

This study shows that astrocyte-specific deletion of Bmal1 disrupts circadian rhythms in perineuronal nets, synaptic plasticity, and learning behavior.

This study shows that traumatic brain injury causes severe and prolonged meningeal lymphatic dysfunction, leading to increased neuroinflammation and cognitive deficits.

This study shows BMAL1 regulates astrocyte activation and function through cell-autonomous and non-cell-autonomous mechanisms, impacting neuronal survival and brain health.