Maxine L. Wang

The paper identifies TXNDC15 as a regulator of ER membrane protein quality control, showing it modulates MARCHF6 to prevent degradation of critical ciliary proteins, thereby affecting ciliogenesis.

The paper describes an automated system for producing secreted proteins in transfected mammalian cells, enabling high-throughput, flexible, and cost-effective protein production for research.

The paper introduces a multiplex method to screen CSP extracellular interactions using nanoparticles and fluorescent beads, showing improved sensitivity and dynamic range over ELISA-based assays.

The paper studies the biogenesis of ER membrane proteins, identifying the EMC and BOS complex as key players and proposing a model for coordinated insertion.

The paper introduces a dual sgRNA library design for CRISPRi screens to identify genetic modifiers, showing improved sensitivity and specificity in detecting epistatic relationships.