Author

Vy N. Nguyen

California Institute of TechnologyORCID 0000-0002-7563-7386Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Vy N. Nguyen1 paper · Seattle Children's Research Institute

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

Alina GunaiD· 2 shared Katharine R. PageiD· 2 shared Maxine L. WangiD· 2 shared R. M. VoorheesiD· 2 shared Tsui‐Fen ChouiD· 2 shared Adarsh K. Mayank· 1 shared Giovani Pinton TomaleriiD· 1 shared Jacob M. KirshiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Alina GunaORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 2, 2026

TXNDC15 modulated quality control at the endoplasmic reticulum shapes ciliogenesis

Vy N. Nguyen, Lena A. K. Bögeholz, Katharine R. Page…·R.M. Voorhees

The paper identifies TXNDC15 as a regulator of ER membrane protein quality control, showing it modulates MARCHF6 to prevent degradation of critical ciliary proteins, thereby affecting ciliogenesis.

DOI 10.64898/2026.04.01.715963

humanproteomics

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BiochemistryACS Chemical BiologyPeer-reviewedMar 17, 2026

Structures of bacterial and human phosphoglycosyltransferases bound to a common inhibitor inform selective therapeutics

Yusrah B. Kaudeer, Jacob M. Kirsh, Katsuhiko Mitachi…·William Clemons

The paper determines cryo-EM structures of APPB bound to MraY and DPAGT1, revealing conformational differences that guide the design of selective therapeutics for antibacterial and anticancer applications.

DOI 10.1021/acschembio.5c01037

bacteria (other)human

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Cell BiologyMolecular CellPeer-reviewedAug 22, 2024

Role of a holo-insertase complex in the biogenesis of biophysically diverse ER membrane proteins

Katharine R. Page, Vy N. Nguyen, Tino Pleiner…·R. M. Voorhees

The paper studies the biogenesis of ER membrane proteins, identifying the EMC and BOS complex as key players and proposing a model for coordinated insertion.

25 citations

humanproteomics

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