ImmunologybioRxivPreprint
Macrophages Lacking TSC2 have mTORC1-dependent GPNMB Augmentation Ameliorating Cardiac Ischemia-Reperfusion Injury
Mohammad Keykhaei, Navid Koleini, Mariam Meddeb…·David A. Kass
This study shows that macrophages with constitutive mTORC1 activation via TSC2 deletion reduce inflammation and improve cardiac function after ischemia-reperfusion injury by increasing GPNMB expression.
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